In China, natural gas storages in salt rock are going to be built in a large scale. This project is carried out aiming at the key scientific issue in surface deformation prediction above the natural gas storages. In order to realize the space-time development prediction of surface deformation, the methods of theory analysis, model tests, numerical simulation, and measured data feedback are used comprehensively. Main research contents are as follows: through widely investigation on the geological environment of salt rock, the typical geological features of overlying strata are summarized. Combined with the operation principle, process and safety requirements of the natural gas storage, typical formation conditions and running conditions are tried out. By using model tests and numerical simulation, the deformation mechanism of spatial response and conduction, as well as time response and conduction between adjacent strata are analyzed, and the characteristics and laws of spatial response and time response are received. Then, the initial prediction model is built, which can reflect the time-space development of the surface deformation. Based on the existing monitoring data of the surface deformation, the initial prediction model is tested and modified, and the modified prediction model can be obtained. The modified prediction model could be used to instruct the site selection, construction and safety evaluation of the natural gas storages in salt rock.