Submarine landslides are a geological hazard that may cause significant damage, and are among the most serious problems in offshore geotechnics. Understanding the mechanism of submarine landslide/offshore structure interaction is essential for risk assessment, but it is challenging due to its complexities. In this study, ten centrifuge tests were conducted to determine how offshore wind turbines founded on four piles respond to consecutive submarine landslides. The tests highlighted two mechanisms of soil deformation and foundation settlement associated with the landslide cycle: (1) deformations of the clay were associated with induced excess pore water pressure, and increased with the number of landslides; and (2) by contrast, foundation settlements largely depended on the dynamic impact of the first cycle and remained unchanged for the remaining events. The settlements were 0.5 m for the 10 m pile foundation and about 0.1 m for the 20 m pile foundation, both in clay and in sand. It was also found that increasing pile length reduces the excess pore water pressure, soil deformation and foundation settlement.