Volcanoes, during their explosive and post-explosive phases, as well as through continuous degassing processes, release a range of pollutants hazardous to human health, including toxic gases, fine particulate matter, and heavy metals. These emissions impact over 14% of the global population living in proximity to volcanoes, with effects that can persist for days, decades, or even centuries. Living conditions in these regions often involve chronic exposure to contaminants in the air, water, and soil, significantly increasing the risk of developing neurological disorders. Prolonged exposure to elements such as lead (Pb), mercury (Hg), and cadmium (Cd), among others, results in the accumulation of metals in the brain, which increases oxidative stress and causes neuronal damage and severe neurotoxicity in animals. An examination of metal accumulation in brain cells, particularly astroglia, provides valuable insights into the developmental neurotoxicity of these metals. Moreover, microglia may activate itself to protect from cytotoxicity. In this review, we consider the implications of living near an active volcano for neurotoxicity and the common neurodegenerative diseases. Additionally, we encourage governments to implement public health strategies and mitigation measures to protect vulnerable communities residing near active volcanoes.

Ethiopia's vulnerability to climate change is exacerbated by high poverty rates, rapid population growth, increasing prevalence of vector-borne diseases, and heavy reliance on rain-fed agriculture. This narrative review aims to compile existing data on the impacts of climate extremes on the physical environment, public health, and livelihoods in Ethiopia, thereby highlighting the significance of this region for such a study. Data were sourced from peer-reviewed journal articles from databases like PubMed, Scopus, and Web of Science, as well as reports and other unpublished documents. Results show that Ethiopia is facing increasing frequency, severity, duration, and timing of climate-related extreme events. Key challenges include environmental degradation, reduced crop yields, recurring floods, droughts, famines, increased heat waves, and spread of infectious diseases. Average daily rainfall is projected to decrease from 2.04 mm (1961-1990) to 1.97 mm (2070-2099), indicating a worsening climate trend. Moreover, the average annual temperature has risen by 1.3 degrees C since 1960, at a rate of 0.28 degrees C per decade. Flood records indicate a sharp rise, with 274 flood incidents recorded in 2020, causing extensive damage, including an annual soil loss of 1 billion tons in the Ethiopian highlands, reducing land productivity by 2.2% annually. Droughts from 1964 to 2023 affected 96.5 million people, reduced GDP by 4%, decreased agricultural output by 12%, and increased inflation rates by 15%. The regions of Afar, Somali, Gambella, and Benshangul Gumuz exhibit extreme vulnerability to health impacts due to rising temperatures. Addressing climate extremes is critical to mitigate their adverse effects on Ethiopia's environment, public health, and livelihoods.

Environmentally persistent free radicals are long-lived pollutants that maintain stability in air, soil, and water. They contribute to the production of reactive oxygen species in environmental media, leading to oxidative stress in biological organisms. This stress can provoke inflammation and damage to biological macromolecules, potentially resulting in cardiopulmonary dysfunction. In this review, we discuss the formation and classification of EPFRs. Typically, EPFRs form through electron transfer from organic compounds to transition metals during thermal processes. In metal-free environments, however, organic compounds can undergo bond cleavage, generating EPFRs under thermal conditions and light exposure. EPFRs are generally categorized into three types: oxygen-centered, carbon-centered, and those containing heteroatoms centered on either oxygen or carbon. We also provide a detailed summary of the fundamental characteristics of EPFRs in different environments such as air, soil, and water. Given their role as electron donors, EPFRs have potential applications in degrading organic pollutants in the environment. The review comprehensively addresses the deleterious impacts of EPFRs on organism health, highlighting risks to metabolic functions and cardiopulmonary health. Furthermore, it underscores the potential involvement of EPFRs as electron donors in atmospheric chemical reactions. The pivotal role of EPFRs in environmental pollutant transformation warrants more studies in future research endeavors.

Atmospheric aerosols are important from a perspective of ambient air pollution and health to humans and other biological receptors as well as for potential effects on local weather and global climate. This review attempts to account for the different research efforts of individual research groups and regulatory agencies in India on the issue of atmospheric aerosols and their effects. The review refers to representative studies reporting the physical characterization (size), chemical composition (organic and inorganic), radiative forcing effects and health effects of aerosols. There are several reports on source apportionment studies identifying sources of aerosols and some focus on specific issues. The review also points out a significant need for more data with a greater spatial and temporal resolution for better understanding of the dynamics of atmospheric aerosols in the Indian context.