Corn rootworms (CRW) are among the most destructive pests in corn production across the Corn Belt, causing considerable damage through larval feeding on roots. While crop rotation and Bt technologies are widely adopted management strategies, their effectiveness is increasingly compromised by the pest's evolution of resistance and behavioral adaptability. Chemical insecticides applied at planting to target larvae directly serve as an additional tool for corn rootworm control. In this study, we evaluated the performance of various insecticides, applied in-furrow, for managing corn rootworms by assessing Node Injury Scale (NIS), lodging rates, and grain yields from 2020 to 2024. We found that Mode of Action (MOA) 3A insecticides (sodium channel modulators), such as Force Evo (tefluthrin) and Capture LFR (bifenthrin), did not provide substantial efficacy in reducing NIS and lodging rates. In contrast, MOA 1B+3A insecticides (acetylcholinesterase (AChE) inhibitors + sodium channel modulators), such as INDEX (chlorethoxyfos + bifenthrin) and AZTEC HC (tebupirimphos + cyfluthrin), significantly reduced CRW larval damage, particularly under high pest pressure in 2020, 2021 and 2023. Differences in insecticide concentrations did not significantly impact larval control efficacy. Additionally, seasonal rainfall during larval hatching and variation in cumulative corn growing degree days (GDD) strongly influenced the root injury and lodging outcomes. Lower GDD likely limits root regeneration, increasing lodging risk under CRW pressure. These findings demonstrate the values of in-furrow insecticides in managing corn rootworms, particularly under high pest pressure and provide valuable insights for developing integrated pest management strategies to sustain effective CRW larval control and improve crop productivity.