Sugar maple, an economically and ecologically important tree in the northern hardwood forest, has experienced regeneration failure that in the Northeast portion of the range has been variously attributed to soil acidification and resultant changes in soil chemistry, impacts of climate change, and effects of species composition. In a 5-year study spanning a latitudinal gradient in the state of New Hampshire, we examined evidence for these three hypotheses to explain sugar maple regeneration patterns. Overall, sugar maple seedling survival was highest in the two sites with lower sugar maple abundance. Alternatively, the two other sites with greater than 50% sugar maple relative dominance shared the following outcomes: higher seed production per area, greater foliar pest damage, lower seedling survival, lower sapling density, and higher canopy maple mortality, while the sites with lower dominance of maple had opposite outcomes. Based on field data and a common garden experiment, conspecific impacts on seedling survival were related to foliar pests and fungal pathogens rather than through soil feedbacks. These results lend support to other studies encouraging promotion of stand tree diversity and avoidance of monocultures.