This paper presents a comprehensive approach encompassing indoor exper-iments, theoretical analysis, and numerical simulations to investigate thedurability of prestressed anchorage structures subjected to fatigue loads andcorrosion. The study addresses the critical issue of gradual aging and dam-age caused by cumulative loads and corrosion, which ultimately leads to adecrement in structural durability. Through a rigorous analysis of the effectsof fatigue load and corrosion on the performance of steel bars, numericalsimulations were conducted to elucidate the failure mechanisms and variationpatterns within the internal anchoring section. After subjecting steel bars tofatigue and corrosion tests for a defined duration, they were systematicallycategorized and exposed to varying fatigue tensile cycles in diverse acidic andalkaline environments. Employing the PFC2D program, a numerical modelof the prestressed anchorage structure under the coupled effects of fatigueload, corrosion, and fatigue load was developed. This model allowed for acomparative analysis of the evolution of shear stress, axial stress, and dis-placement fields at the bolt-grout interface under two distinct conditions. The findings reveal the microscopic mechanisms underlying bond degradationat the bolt-grout interface under the synergistic impact of fatigue load andcorrosion. The proposed methodology and experimental results demonstratethat geotechnical anchoring technology can effectively reinforce up to 70%of geotechnical structures, significantly reducing soil loss by approximately80%. This research provides valuable insights into the durability of pre-stressed anchorage structures, paving the way for future improvements andoptimizations.