Lunar core samples are the key materials for accurately assessing and developing lunar resources. However, the difficulty of maintaining borehole stability in the lunar coring process limits the depth of lunar coring. Here, a strategy of using a reinforcement fluid that undergoes a phase transition spontaneously in a vacuum environment to reinforce the borehole is proposed. Based on this strategy, a reinforcement liquid suitable for a wide temperature range and a high vacuum environment was developed. A feasibility study on reinforcing the borehole with the reinforcement liquid was carried out, and it is found that the cohesion of the simulated lunar soil can be increased from 2 to 800 kPa after using the reinforcement liquid. Further, a series of coring experiments are conducted using a self-developed high vacuum (vacuum degree of 5 Pa) and low-temperature (between -30 and 50 degrees C) simulation platform. It is confirmed that the high-boiling-point reinforcement liquid pre-placed in the drill pipe can be released spontaneously during the drilling process and finally complete the reinforcement of the borehole. The reinforcement effect of the borehole is better when the solute concentration is between 0.15 and 0.25 g/mL. (c) 2025 Published by Elsevier B.V. on behalf of China University of Mining & Technology. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).