Soil heavy metal pollution caused by mining in mining areas seriously affects crop yield and causes human diseases. It is necessary to prevent soil heavy metal pollution from damaging health. Hyperspectral remote sensing can rapidly and dynamically acquire continuous spectra signals of ground objects, which provides a new idea for developing soil heavy metal content monitoring based on remote sensing. Aiming at the typical lead-zinc mining area in Laiyuan County, Hebei Province, soil samples from the mining area and surrounding areas are collected on-site, and the reflectance spectra of soil were obtained using SVC HR-1024i spectrometer (350 similar to 2 500 nm). Through the spectral data smoothing, first derivative (FD), multivariate scattering correction (MSC), standard normal variate transform (SNV), first derivative after multivariate scattering correction (MSC+FD), and first derivative after standard normal variatetrans form (SNV+FD), six kinds of spectral transformations were performed. The difference index (DI), ratioindex (RI), and normalized difference index (NDI) methods were used to extract the The optimal independent variables for different heavy metal elements were selected to increase the practical features of inversion modeling. Random forest algorithm and partial least squares regression method were used to establish prediction models for three heavy metals: cadmium (Cd), lead (Pb) and zinc (Zn) in soil. (Pb), and zinc (Zn). The R-2 of the optimal models reached 0.90, 0.91, and 0.84, respectively, which confirmed the validity of this research method. This study can provide a basis for the inversion modeling of soil heavy metal content in lead-zinc mining areas and a method reference for detecting soil heavy metal content in mining areas.