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Permafrost is one of the crucial components of the cryosphere, covering about 25% of the global continental area. The active layer thickness (ALT), as the main site for heat and water exchange between permafrost and the external atmosphere, its changes significantly impact the carbon cycle, hydrological processes, ecosystems, and the safety of engineering structures in cold regions. This study constructs a Stefan CatBoost-ET (SCE) model through machine learning and Blending integration, leveraging multi-source remote sensing data, the Stefan equation, and measured ALT data to focus on the ALT in the Qinghai-Tibet Plateau (QTP). Additionally, the SCE model was verified via ten-fold cross-validation (MAE: 20.713 cm, RMSE: 32.680 cm, R2: 0.873, and MAPE: 0.104), and its inversion of QTP's ALT data from 1958 to 2022 revealed 1998 as a key turning point with a slow growth rate of 0.25 cm/a before 1998 and a significantly increased rate of 1.26 cm/a afterward. Finally, based on multiple model input factor analysis methods (SHAP, Pearson correlation, and Random Forest Importance), the study analyzed the ranking of key factors influencing ALT changes. Meanwhile, the importance of Stefan equation results in SCE model is verified. The research results of this paper have positive implications for eco-hydrology in the QTP region, and also provide valuable references for simulating the ALT of permafrost.

来源平台：REMOTE SENSING