Tribochemistry is defined as the reaction induced by mechanical energy. The physical or chemical reaction would be happened at the interface when two contact surfaces sliding against each other. The tribochemistry reaction of the lubricants in their service process has positive or negative impact to their properties. It is valuable through probing the tribochemistry reaction mechanism, the structure and composition of reaction products to understand the failure mechanism and the theory of property regulation of lubricants. Aiming at main kinds of lubricants including oil additives, nanoparticle additives, ionic liquids, rare earth, ceramics, diamond like carbon films, organic thin films and polymers, the studies on the tribochemistry of the lubricants in the last few decades are reviewed.