The preparation of a single crystal superalloy surface overlay welding coating to improve its high-temperature mechanical properties is of great significance for prolonging the service life of blades. This work selected two types of welding wire alloys, CoCrMo and CoCrW, to prepare coatings on the surface of a single crystal superalloy. A comparative study was conducted on their mechanical properties, such as tension, compression, fatigue, durability, and wear at a high temperature of 900 ℃, aiming to reveal the high-temperature mechanical properties of the two types of welding coatings. Results showed that the average high-temperature tensile strength of the CoCrMo welded specimen was smaller than that of the CoCrW welded specimen; the average high-temperature duration of CoCrMo welded specimens at 150 MPa was lower than the average duration of CoCrW welded specimens; the high-temperature fatigue life of CoCrMo welded specimens at 220 MPa was 7.186 × 10 5; and the average high-temperature wear rate of CoCrMo sample was 3.64 × 10 −6 mm 3·N −1·m −1. The CoCrW alloy was more wear resistant than CoCrMo. The hardness of CoCrMo welded joints gradually increased from the substrate to the heat-affected zone and then to the fusion zone, and was much higher in the fusion zone than in the CoCrW alloy.