Understanding atomic friction within a liquid environment is crucial for engineering friction mechanisms and characterizing surfaces. It has been suggested that the lattice resolution of friction force microscope in liquid environments stems from a dry contact state, with all liquid molecules expelled from the area of closest approach between the tip and substrate. Here, we revisit this assertion by performing in-depth friction force microscopy experiments and molecular dynamics simulations of the influence of surrounding water molecules on the dynamic behavior of the nanotribological contact between an amorphous SiO2 probe and a monolayer MoS2 substrate. An analysis of simulation and experimental stick–slip patterns demonstrates the entrapment of water molecules at the contact interface. These trapped water molecules behave as an integral component of the probe and participate in its interaction with the substrate, affecting the dynamics of the probe and preventing long slips. Significantly, surrounding water from the capillary or layer exhibits a replenishing effect, acting as a water reservoir during sliding. This phenomenon facilitates the preservation of lattice-scale resolution across a range of applied normal loads.