With increasing environmental awareness, the demand for bio-based lubricants is escalating, positioning vegetable oils as viable alternatives to traditional industrial lubricants. This study is based on the previously established quantitative structure-property relationship - multiple linear regression (QSPR-MLR) model. Then, it employs comprehensive factor scores to assess and rank the anti-wear properties and oxidation stability of 53 vegetable oils with diverse fatty acid compositions. Xanthoceras sorbifolia Bunge oil (XSBO), derived from woody oil plants renowned for their economic and environmental benefits, emerges as a standout candidate following exclusion of previously reported lubricant types. Comparative evaluations via four-ball friction tests and pressurized differential scanning calorimeter (PDSC) analyses reveal XSBO's antioxidant properties are slightly inferior to mineral oils, poly-a-olefins, and synthetic esters. However, XSBO exhibits superior tribological properties and viscosity characteristics. Supported by computational modeling and laboratory validation, XSBO demonstrates significant promise as a bio-based lubricant, advocating its potential as an ideal replacement for conventional base oils.