Wirelessly driven flexible actuators are crucial to the development of flexible robotic crawling. However, great challenges still remain for the crawling of flexible actuators in complex environments. Herein, we reported a wireless flexible actuator synergistically driven by wireless power transmission (WPT) technology and near-infrared (NIR) light, which consists of a poly(dimethylsiloxane)–graphene oxide (PDMS-GO) composite layer, eutectic gallium–indium alloy (EGaIn), a PDMS layer, and a polyimide (PI) layer. By optimizing the parameters of EGaIn and the concentration of the PDMS-GO composite film, the actuator has excellent bending ability and blocking force under different conditions driven by photoelectronic synergy. In addition, we fabricated a flexible crawling robot with high environmental adaptability by adding crawling structures at both ends of the actuator, which causes a discrepancy in friction between the front and rear feet. The flexible crawling robot has high stability, large deformation, and excellent crawling ability for wirelessly crawling on a plane, slope, and plane with different roughnesses. This work provides an idea for the application of wireless robots in complex environments.