Poly lactic Acid (PLA) has gained much attention worldwide for its application in bio medical sector, especially in scaffolds and joint replacements. Various nano fillers have been incorporated into PLA matrix to improve the mechanical, tribological and biocompatibility behavior of the polymer. This work discusses on the mechanical and tribological behavior of PLA composites reinforced with nano zirconia prepared via Fused filament deposition (FFD). Mechanical properties of the additively manufactured composites were determined by means of tensile testing according to ASTM standards. Mechanical degradation of the specimens was assessed using in-vitro testing of the materials in Simulated body fluid condition (SBF). Influence of nano zirconia on tribological behavior have been analyzed using pin-on-disc tribometer under SBF lubrication. Results show that addition of nano zirconia improved tensile strength considerably. Tribological tests reveal that addition of nano zirconia enhances the wear resistance and also reduces the friction coefficient. PLA exhibits adhesion as well as plastic deformation, whereas abrasion and oxidation seem to major wear mechanism involved in case of PLA composites.