Critical moving components frequently encounter significant tribocorrosion challenges during service. Nevertheless, conventional protective coatings typically perform inadequately under wear-corrosion coupling conditions, exhibiting rapid degradation and concealed failure. Here, a high-performance filler (AR-FM) is synthesized by in-situ growth of MIL-100(Fe) nanocontainers on 2D transition metal carbides Ti 3C 2T x MXene nanosheets, with the simultaneously encapsulating 5-amino-1,3,4-thiadiazole-2-thiol (AMT) and Rhodamine B (RhB). Subsequently, AR-FM is incorporated into an epoxy matrix to fabricate a smart protective coating (FMP). The tribocorrosion resistance of FMP with pH/mechanical dual-stimulus response and the relevant protective mechanisms are investigated through the combined use of experiments and molecular dynamics simulations. Under the tribocorrosion conditions, the wear rate of FMP (8.29 × 10 -6 mm 3/N·m) is one order of magnitude lower than that of the epoxy coating (EP), and its open-circuit potential remains a high level with minimal fluctuations (ΔV OCP < 0.005 V). When exposed to corrosive conditions, the complexation of released RhB with Fe 3+ causes fluorescence quenching for self-warning, while the released AMT forms a passivation film at the damaged site, leading to the self-healing efficiency of 99.9 ± 0.05%. The excellent tribocorrosion resistance is attributed to the synergistic effect of enduring MXene-based lubricating film, enhanced deformation resistance, strong interfacial bond strength, and efficient corrosion resistance with dual pH/mechanical stimulus response.