Ti 3C 2T x nanosheets have showed great potential application in corrosion prevention and wear resistance fields due to their large specific surface area and high mechanical properties. But, a critical challenge for the application of Ti 3C 2T x nanosheets is the susceptibility to oxidation in aqueous condition. Structural changes are bound to have a significant impact on physical and chemical properties, whether it is a positive or negative effect, and opinions vary, even contradictory. This study aims to clarify the influence of the oxidation degree of Ti 3C 2T x nanosheets on their corrosion and wear resistant behaviors. By regulating the oxidation time, three kinds of oxidized nanosheets were obtained, including slight (M-O 15min), moderate (M-O 12h) and severe (M-O 48h) oxidation. Furthermore, Ti 3C 2T x and the oxidized nanosheets were modified with polydopamine (PDA) to enhance their compatibility with waterborne epoxy (EP). After seven cycles of AHP immersion under 100 MPa, |Z| 0.01Hz of M@P/EP and M-O 48h@P/EP coatings was 2.49×10 8 Ω‧cm 2 and 7.06×10 7 Ω‧cm 2, which were five and four orders of magnitude higher than that of M-O 15min@P/EP coating (5.27×10 3 Ω‧cm 2), respectively. Meanwhile, M@P/EP and M-O 48h@P/EP coatings exhibited lower wear rates of 1.51×10 -3 mm 3 N -1 m -1 and 1.10×10 -3 mm 3 N -1 m -1 compared to M-O 15min@P/EP coating (1.96×10 -3 mm 3 N -1 m -1), respectively. Interestingly, with increasing oxidation degree of Ti 3C 2T x nanosheets, the corrosion prevention and wear resistance of Ti 3C 2T x reinforced coatings firstly decreased then increased. This work systematically reveals how structural changes in Ti 3C 2T x nanosheets affect corrosion prevention and wear resistance, providing valuable guidance for their actual application.